What medicine should I take if I have gout for more than 20 days?
Gout is a common metabolic disease, mainly caused by the deposition of uric acid crystals in the joints, which manifests as joint redness, swelling, and severe pain. For patients with gout attacks that last more than 20 days, rational use of medication is key. This article will combine the hot topics and hot content on the Internet in the past 10 days to provide you with detailed medication suggestions and precautions.
1. Commonly used drugs for acute gout attacks
An acute attack of gout usually lasts 1-2 weeks, but in some patients it may last more than 20 days. The following are commonly used drugs during the acute phase:
| Drug name | Mechanism of action | Usage and dosage | Things to note |
|---|---|---|---|
| Nonsteroidal anti-inflammatory drugs (NSAIDs) | Inhibits prostaglandin synthesis, reducing inflammation and pain | Such as ibuprofen 400mg, 3 times a day | Use with caution in those with gastrointestinal discomfort |
| colchicine | Inhibit leukocyte chemotaxis and reduce inflammatory response | 1mg initially, then 0.5mg every 2 hours, no more than 6mg daily | Diarrhea and nausea may occur |
| Glucocorticoids | Anti-inflammatory, immunosuppressive | For example, prednisone 20-40mg/day, gradually reduce the dose | Long-term use requires monitoring for side effects |
2. Uric acid-lowering treatment for chronic gout
If a gout attack lasts for more than 20 days, it may have entered the chronic phase, and uric acid-lowering treatment needs to be considered. The following are commonly used medications:
| Drug name | Mechanism of action | Usage and dosage | Things to note |
|---|---|---|---|
| Allopurinol | Inhibit uric acid production | Initial 100mg/day, gradually increase to 300mg/day | Liver function needs to be monitored |
| febuxostat | Selectively inhibits xanthine oxidase | 40-80mg/day | Use with caution in patients with cardiovascular disease |
| Benzbromarone | Promote uric acid excretion | 50-100mg/day | Drink more water and monitor urine pH |
3. Dietary recommendations for gout patients
In addition to medication, dietary modification is also very important. The following are foods that gout patients should avoid and recommend:
| food category | Foods to avoid | Recommended food |
|---|---|---|
| meat | Offal, red meat | Chicken and fish (appropriate amount) |
| seafood | Sardines, shellfish | Sea cucumber, jellyfish |
| drinks | Alcohol, sugary drinks | water, lemonade |
4. Lifestyle management after a gout attack for more than 20 days
1.drink more water: Drink 2000-3000ml of water daily to promote uric acid excretion.
2.moderate exercise: Avoid strenuous exercise and choose low-intensity exercise such as walking and swimming.
3.control weight: Obesity will increase the production of uric acid, so weight needs to be controlled through healthy diet and exercise.
4.Regular monitoring: Regularly check blood uric acid levels and adjust medication regimen.
5. Hot topics about gout in the past 10 days on the Internet
1.The relationship between gout and cardiovascular disease: Studies have found that gout patients have a higher risk of cardiovascular disease and require comprehensive management.
2.Progress of new uric acid-lowering drugs: New drugs such as URAT1 inhibitors are in clinical trials.
3.Mental health of gout patients: Long-term pain may lead to anxiety and depression, so you need to pay attention to your mental state.
Summary
Gout attacks that last more than 20 days require a combination of acute and chronic treatment, rational use of medication, and lifestyle adjustments. It is recommended to choose appropriate drugs under the guidance of a doctor and adhere to long-term management to reduce the risk of gout recurrence and complications.
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