What diseases does cilostazol tablets treat?
Cilostazol tablets are a commonly used clinical antiplatelet aggregation drug, mainly used to treat peripheral arterial disease and prevent thrombosis. In recent years, with the increase in the incidence of cardiovascular and cerebrovascular diseases, the application of cilostazol tablets has also received widespread attention. This article will combine the hot topics and hot content on the Internet in the past 10 days to introduce in detail the indications, mechanism of action, usage, dosage, and precautions of cilostazol tablets.
1. Indications of Cilostazol Tablets
The main indications for cilostazol tablets include:
| Indications | illustrate |
|---|---|
| intermittent claudication | It is used to improve the symptoms of intermittent claudication caused by peripheral arterial disease and increase the walking distance of patients. |
| Prevent thrombosis | Used to prevent atherosclerotic thrombosis and reduce the risk of cardiovascular and cerebrovascular events. |
| chronic arterial occlusive disease | Used to improve blood circulation and relieve symptoms in patients with chronic arterial occlusive disease. |
2. The mechanism of action of cilostazol tablets
Cilostazol is a phosphodiesterase III (PDE3) inhibitor. By inhibiting the activity of PDE3, it increases the concentration of intracellular cyclic adenosine monophosphate (cAMP), thereby exerting the following effects:
| Mechanism of action | Effect |
|---|---|
| Anti-platelet aggregation | Inhibit platelet aggregation and prevent thrombosis. |
| vasodilation | Expand peripheral blood vessels and improve blood circulation. |
| anti-inflammatory effect | Reduce the inflammatory response of blood vessel walls and protect vascular endothelial function. |
3. Usage and dosage of cilostazol tablets
The conventional usage and dosage of cilostazol tablets are as follows:
| usage | Dosage | Things to note |
|---|---|---|
| oral | 50-100mg each time, 2 times a day | It can be taken before or after meals, but avoid taking it with grapefruit juice. |
| Course of treatment | Adjust according to the condition and usually need to be taken for a long time | Regularly review platelet function and liver function. |
4. Precautions when using cilostazol tablets
When using cilostazol tablets, please note the following:
| Things to note | Detailed description |
|---|---|
| Contraindications | It is contraindicated in those who are allergic to cilostazol, those with severe hepatic insufficiency, and pregnant women. |
| adverse reactions | Common symptoms include headache, palpitations, gastrointestinal discomfort, etc., and bleeding tendencies may occur in severe cases. |
| drug interactions | Combination with anticoagulants and antiplatelet drugs may increase the risk of bleeding, so caution is required. |
5. Hot topics on the Internet in the past 10 days and discussions related to cilostazol tablets
In the past 10 days, discussions about cilostazol tablets have mainly focused on the following aspects:
| hot topics | Discussion content |
|---|---|
| Comparison of Cilostazol Tablets and Aspirin | Netizens are hotly discussing the advantages and disadvantages of cilostazol tablets and aspirin in antiplatelet treatment. Some experts believe that cilostazol is more suitable for patients with peripheral artery disease. |
| Long-term safety of cilostazol tablets | Some studies have pointed out that long-term use of cilostazol tablets may have a certain impact on liver function, and regular monitoring is recommended. |
| Exploration of new indications for cilostazol tablets | Some clinical trials are exploring the potential role of cilostazol tablets in the prevention of diabetic foot and cerebral infarction. |
6. Summary
Cilostazol tablets are an effective anti-platelet aggregation drug, mainly used to treat peripheral arterial disease and prevent thrombosis. It works by inhibiting PDE3 and has multiple effects such as anti-platelet aggregation, vasodilation and anti-inflammatory. Pay attention to contraindications, adverse reactions and drug interactions when using it. Recent discussions on cilostazol tablets across the Internet have mainly focused on comparison with aspirin, long-term safety and exploration of new indications. Patients should use this drug rationally under the guidance of a doctor to achieve the best therapeutic effect.
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